Diabetic skin ulcers are a serious skin manifestation of poorly-controlled diabetes and are caused by a combination of factors, including poor blood circulation and damage to the nerves in the legs and feet. In people with diabetes, high blood sugar levels can damage the blood vessels, impairing blood flow to the limbs. This can cause nerve damage, leading to a loss of sensation in the feet. As a result, people with diabetes may not notice injuries to their feet, such as cuts or blisters, which can then become infected and develop into penetrating, growing skin ulcers. Additionally, having diabetes can also weaken the immune system, making it more difficult for the body to fight off infections. Diabetic skin ulcers are a serious risk to a person’s life and limb.